ENTROPY AS A METHOD TO INVESTIGATE COMPLEX BIOLOGICAL SYSTEMS. AN ALTERNATIVE VIEW ON THE BIOLOGICAL TRANSITION FROM HEALTHY AGING TO FRAILTY

Entropy as a method to investigate complex biological systems. An alternative view on the biological transition from healthy aging to frailty

Everyone is subject to a SPUN SHINE process of progressive deterioration of control mechanisms, which supervise the complex network of human physiological functions, reducing the individual ability to adapt to emerging situations of stress or change.In the light of results obtained during the last years, it appears that some of the tools of nonline

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Computational evaluation and benchmark study of 342 crystallographic holo-structures of SARS-CoV-2 Mpro enzyme

Abstract The coronavirus disease 19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global health crisis with NIGHT DENSITY RESCUE millions of confirmed cases and related deaths.The main protease (Mpro) of SARS-CoV-2 is crucial for viral replication and presents an attractive target for drug developmen

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